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The Research Behind Red Light Therapy

The science of
light reaching deeper

Peer-reviewed research on red light therapy, collagen production,
and photobiomodulation.
Primary Wavelengths — 640nm & 690nm Red Light
How it works

Light your cells can actually use

Your skin cells run on energy. When red light at the right wavelength reaches the dermis, it's absorbed by the mitochondria — your cells' power source — and converted into usable energy. With more energy available, skin cells repair faster, fibroblasts produce more collagen, and the structural proteins that keep skin firm and smooth begin to rebuild. This process is called photobiomodulation, and it's one of the most studied non-invasive approaches in dermatology.

The velumā mask aims to deliver red light therapy at both 640nm and 690nm (plus 5 additional wavelengths), targeting the dermis where collagen is produced — the layer your skincare products usually cannot reach. Starting in your 30's, collagen production has been estimated to decrease by roughly 1% per year.

01

Light enters the dermis

640nm & 690nm red light penetrates to the dermal layer, where fibroblasts and collagen networks are located.

02

Mitochondria absorb the energy

Cytochrome c oxidase absorbs the light, boosting ATP production — the cellular fuel that powers repair.

03

Fibroblasts activate

Energized fibroblasts increase output of type-1 collagen and elastin — the structural proteins that keep skin firm.

04

Collagen density improves

With consistent use, measurable increases in intradermal collagen density have been documented in clinical settings.

Peer-Reviewed Evidence

Published research on red light therapy & skin rejuvenation

2023 Photobiomodulation, Photomedicine, and Laser Surgery

Photobiomodulation Reduces Periocular Wrinkle Volume by 30%: A Randomized Controlled Trial

Mota LR, Duarte IDS, Galache TR, et al.

A split-face randomized controlled trial of 137 women found that 10 sessions of red (660nm) photobiomodulation produced a 31.6% reduction in periocular wrinkle volume, measured using objective 3D imaging equipment. Both quality-of-life scores improved significantly. No adverse events were reported.

PubMed ↗
2009 Journal of Investigative Dermatology

Regulation of skin collagen metabolism in vitro using a pulsed 660nm LED light source: clinical correlation with a single-blinded study

Barolet D, Roberge CJ, Auger FA, Boucher A, Germain L.

LED treatment at 660nm produced a 31% increase in type-1 procollagen levels and an 18% decrease in MMP-1 (an enzyme that degrades collagen) compared to untreated controls. Over 90% of participants showed reduced skin roughness and 87% experienced a reduction in the Fitzpatrick wrinkling severity score after 12 treatments. No adverse events reported.

PubMed ↗
2019 Journal of the American Academy of Dermatology

Low-level red and infrared light increases expression of collagen, elastin, and hyaluronic acid in skin

Published in JAAD.

LED treatment with red and infrared light significantly increased hyaluronic acid synthase (HAS2) and elastin gene expression in human fibroblasts in as little as 3 days. Also demonstrated measurable increases in collagen protein synthesis, supporting the use of low-level LED therapy for photoaging.

View ↗
2014 Photomedicine and Laser Surgery

A controlled trial to determine the efficacy of red and near-infrared light treatment in patient satisfaction, reduction of fine lines, wrinkles, skin roughness, and intradermal collagen density increase

Wunsch A, Matuschka K.

In this prospective, randomized, controlled study of 136 volunteers treated twice weekly, subjects showed significantly improved skin complexion, skin feeling, and profilometrically assessed skin roughness. Ultrasonographic measurements confirmed measurable increases in intradermal collagen density compared to controls.

PubMed ↗
2013 Seminars in Cutaneous Medicine and Surgery

Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring

Avci P, Gupta A, Sadasivam M, et al. — Harvard Medical School / Massachusetts General Hospital

A comprehensive review of laboratory and clinical studies found that red and near-infrared light stimulates fibroblast proliferation and significantly increases collagen synthesis. Identified the mitochondrial pathway (cytochrome c oxidase) as the primary mechanism of action. One of the most widely cited papers in photobiomodulation research.

PubMed ↗
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Important notice about this research

The studies above are independent, peer-reviewed research papers not sponsored or controlled by velumā. We link directly to PubMed or the original journal so you can read the full research yourself. Referenced studies may involve different devices, wavelengths, irradiance levels, or treatment protocols than the velumā mask™. Linking to a study does not constitute a claim that the velumā mask™ replicates those outcomes.

The velumā mask™ is a personal wellness device. It is not a medical device and is not intended to diagnose, treat, cure, or prevent any disease or medical condition. Individual results vary. Always consult a physician before use if you have a diagnosed skin condition or are taking photosensitizing medications.

For complete disclaimers, see our Legal Notice & Disclaimers.

Let your light reach where skincare can't.

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